Act One
The first act covers Elphaba's arrival at Shiz University, her reluctant bond with Galinda, the silencing of the Animals, and the discovery that the Wizard of Oz is a fraud. It ends on a single defiant note: Elphaba, on a broom, defying gravity itself.
The Story, Beat by Beat
- Opening: Glinda, now the public face of Oz, celebrates the death of the Wicked Witch of the West. She corrects the record. The story begins in flashback.
- Elphaba at Shiz: Born green, raised in Munchkinland, sent away by her embarrassed father. The school's most gifted student, ostracised for her colour.
- Galinda arrives: Popular, pampered, in pink. Roommate to Elphaba by accident. Their first meeting is the show's first duet, “What Is This Feeling?”
- Doctor Dillamond is fired: The first casualty of the Wizard's quiet war on the Animals. Elphaba begins to understand what is happening.
- Fiyero appears: A Winkie prince, transferred in, immediately disrupting the social order. He dances, and the whole school dances with him.
- Galinda's makeover of Elphaba: A moment of unexpected generosity; the friendship begins.
- One Short Day: Elphaba and Galinda travel to the Emerald City and meet the Wizard, who reveals himself as a fraud.
- Defying Gravity: Elphaba chooses to be labelled Wicked rather than complicit. She flies. Act One ends.
Act One — Songs
| # | Song | Performed by |
| 1 | No One Mourns the Wicked | Glinda & Citizens of Oz |
| 2 | Dear Old Shiz | Students & Glinda |
| 3 | The Wizard and I | Madame Morrible & Elphaba |
| 4 | What Is This Feeling? | Glinda, Elphaba & Students |
| 5 | Something Bad | Dr. Dillamond & Elphaba |
| 6 | Dancing Through Life | Fiyero, Glinda, Boq, Nessarose, Elphaba |
| 7 | Popular | Glinda |
| 8 | I’m Not That Girl | Elphaba |
| 9 | One Short Day | Elphaba, Glinda & Emerald City citizens |
| 10 | A Sentimental Man | The Wizard |
| 11 | Defying Gravity | Elphaba, Glinda, Morrible & Ozians |
Act Two
The second act spans Elphaba's life as an outlaw, the rise of the public myth of the Wicked Witch, the tragic end of Nessarose, the transformations of Fiyero and Boq, and the two women's final farewell.
The Story, Beat by Beat
- Five years later: Glinda is now the public face of Oz, the Wizard's consort, and Elphaba is the most wanted fugitive in the land.
- Nessarose in Munchkinland: Made Governor by the Wizard, governing harshly. Boq, pitying her, agrees to marry her.
- Fiyero returns: Captured by the Wizard's guards, given a choice: save himself or save Dillamond. He saves Elphaba, and disappears.
- The Wizard and Elphaba meet: The Wizard offers her everything — partnership, a place at his side — if she will work with him. She refuses. He reveals he is her father.
- Nessarose's death: The house falls on her. Her shoes — the Silver Shoes — pass to whoever is standing nearby.
- Boq's transformation: Heartbroken, Boq declares he wants to be hollow. He becomes the Tin Man.
- Fiyero's transformation: Captured, about to be executed, saved by Elphaba. He becomes the Scarecrow.
- For Good: Elphaba melts, ostensibly. Glinda, alone, remembers. The two women say goodbye.
- Finale: Glinda, now truly alone in her power, understands the cost of everything that has happened.
Act Two — Songs
| # | Song | Performed by |
| 1 | Thank Goodness | Glinda, Morrible & Citizens of Oz |
| 2 | The Wicked Witch of the East | Elphaba, Nessarose & Boq |
| 3 | Wonderful | The Wizard & Elphaba |
| 4 | I’m Not That Girl (Reprise) | Glinda |
| 5 | As Long as You’re Mine | Elphaba & Fiyero |
| 6 | No Good Deed | Elphaba |
| 7 | March of the Witch Hunters | Boq & Ozians |
| 8 | For Good | Elphaba & Glinda |
| 9 | Finale | Glinda, Elphaba & Ozians |
★ = signature song / major showstopper. The score is heavily thematic, with two main leitmotifs: Elphaba's theme (originated from Schwartz's 1971 work The Survival of St. Joan) and the “Unlimited” theme (which incorporates the first seven notes of “Over the Rainbow” as a tribute to Harold Arlen).